Being a relatively new pathology, coronavirus infection, due to the multiple organ damage to the body, has many clinical manifestations, including dermatological ones, the study of which is still the subject of research. Since its spread, there have been very few reports of dermatological manifestations of COVID-19 and its cutaneous manifestations in the community. Purpose of the study: is to identify the features of the clinical course of dermatological manifestations in patients who have undergone coronavirus infection. Materials and methods: The study included 108 patients who underwent a comprehensive examination and treatment in the Samarkand regional dermatovenerologic dispensary from July 2020 to July 2021. Some of the patients, for 1 to 20 years, previously suffered from various skin diseases, and were under dispensary supervision, the rest came to us with complaints of skin changes after infection. It was also important for us to study the appearance of new elements of the rash on the skin, their intensity, localization, the degree of spread, depending on the severity of the course of coronavirus infection. Results: As noted earlier, dermatological pathology was not detected in 61 (56.5%) of 108 patients before coronavirus infection. The reason for the occurrence in these patients was the manifestation of a coronavirus infection on the skin. We observed 21 (19.4%) patients with papulosquamous eruptions. We observed 13 (12.03%) patients after coronavirus infection whose dermatological manifestations were in the form of urticaria. Herpetic eruptions occurred in 17 patients (15.7%) and were characterized by the appearance of small vesicles, against the background of edematous and hyperemic skin, which were preceded by itching and burning of the skin. Conclusions: The main dermatological manifestations after coronavirus infection were acrodermatitis-type skin changes, 30.6%, papulosquamous rashes - 19.4% of patients, urticaria - 12.03%. papulo-vesicular eruptions - 12.9% and herpetic eruptions 15.7%.
1. Chen, N, Zhou, M, Dong, X, Qu, J, Gong, F, Han, Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. (2020) 2. Dong, N, Yang, X, Ye, L, Chen, K, Chan, EW-C, Yang, M, et al. Genomic and protein structure modelling analysis depicts the origin and infectivity of 2019-nCoV, a new coronavirus which caused a pneumonia outbreak in Wuhan, China. bioRxiv. (2020) 3. Dong, Y, Mo, X, Hu, Y, Qi, X, Jiang, F, Jiang, Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. (2020) 4. Galván Casas C., Català A., Carretero Hernández G. et al. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. British Journal of Dermatology. 2020. 5. Guan, WJ, Ni, ZY, Hu, Y, Liang, WH, Ou, CQ, He, JX, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. (2020) 6. Reinholz M, French L. Medical education and care in dermatology during the SARS-CoV2 pandemia: challenges and chances. J Eur Acad Dermatology Venereol 2020. 7. Ruan, Q, Yang, K, Wang, W, Jiang, L, and Song, J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. (2020) 8. Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. J Eur Acad Dermatology Venereol 2020. 9. Wu F, Zhao S, Yu B et al. A new coronavirus associated with human respiratory disease in China. Nature 2020; 579: 265– 269.
Tashkenbaeva, Umida A. and Klebleeva, Guzal D.
"FEATURES OF DERMATOLOGICAL MANIFESTATIONS AFTER CORONAVIRUS INFECTION IN PATIENTS WITH PREVIOUSLY INTACT SKIN,"
Central Asian Journal of Medicine: Vol. 2021
, Article 11.
Available at: https://uzjournals.edu.uz/tma/vol2021/iss4/11