Central Asian Journal of Medicine


The article presents an analysis of the literature data on the epidemiology of osteoarticular system injury in diabetes mellitus. Some aspects of the pathogenesis of osteoarticular system disorders in diabetes, as well as the main biochemical diagnostic signs of osteoarticular system disorders in diabetic arthropathy are considered.

First Page


Last Page



1. Adamxanova Z.A., Anvarova Sh.S., Niyazova N.F. Biochemical signs of bone metabolism in the timely diagnosis of bone lesions in patients with diabetes // International Journal of Research.- 2016. - No 7 (49), Part 3.- P.42-45. DOI: 10.18454 / IRJ.2016.49.134 2. Bensman V.M. Surgery for purulent-necrotic complications of diabetic foot - M .: ID "Medpraktika-M", 2015. - 496 p. 3. Vyatkin V.A. Effect of glycosaminoglycans and calcium on bone collagen metabolism in rats with alloxan diabetes // Abstract of the dissertation. ... t.f.n. - Yuj.- Lv. state honey. un-t. Chelyabinsk, 2017, 20p. 4. Dedov I.I., Shestakova M.V., Vikulova O.K. Diabetes mellitus in the Russian Federation: prevalence, morbidity rate, mortality rate, carbohydrate metabolism parameters and structure of hypoglycemic therapy according to the Federal Register of Diabetes, status 2017 // Diabetes mellitus. - 2018. - Volume 21 (3). - Pages 144-159. https://doi.org/10.14341/ DM9686 5. Domenyuk D.A., Davydov B.N., Gilmiyarova F.N., Budaichiev G.M., Ivanyuta O.O. Modern methods of detecting bone lesions in children with diabetes // Medical Alphabet. - 2018. - No 34. - T.4. - B.31-40. 6. Ivchenko L.G., Bykov I.M., Basov A.A., Gilmiyarova F.N., Domenyuk D.A., Budaichiev G.M., Ivanyuta S.O. Development and substantiation of the algorithm for assessing the metabolism of the skeletal system in children with type 1 diabetes // Kuban Scientific Medical Bulletin. - 2018. - Volume 25 (5). - Pages 35-47. 7. Kondratyeva L.V., Popkova T.V. Rheumatic manifestations of diabetes. // Scientific-practical rheumatology.- 2018.- T. 56 (5) .- P. 603-612. https://doi.org/10.14412/1995-4484-2018-603-612 8. Koreyba K.A. Fatal forms of diabetic osteoarthropathy. Surgical aspects // Bulletin of modern clinical medicine. - 2019. - Jil. 12 (5). - 35-40 DOI: 10.20969 / VSKM. 12.12.2019 (5) 9. Maksimova N.V., Bobrov D.S. Diabetic osteoarthropathy (Charcoal foot): pathogenesis, diagnosis and treatment of a rare complication of diabetes mellitus // Department of Traumatology and Orthopedics.- 2013. - № 2 (6) .- P.6-12. 10. Markova N.G. Articular syndrome in common rheumatic diseases associated with diabetes.- Abstract of the dissertation ... Ph.D.- Yaroslavl, 2007.- 23p. 11. Pavlova M.G., Lavrischeva N.V., Gusova A.A., Shipotko M.G. Diabetic osteoarthropathy: clinic, diagnosis and treatment // Clinician. 2007. № 6. C.26-31. 12. Panevin T.S., Alekseeva L.I., Melnichenko G.A. Syndrome of limited mobility of joints in diabetes https://doi.org/10.14412/1995-4484-2020-330-335Saloydinov A.Sh., Jumaeva N.B. Mechanisms of development of bone tissue pathologies in diabetes // Theory and practice of modern science. - 2016. - No 3 (9). - S. 677-680. 13. Safarova S.S. The role of biochemical markers in the diagnosis of bone reconstruction disorders in patients with diabetes // Perm Medical Journal. - 2018.- T. XXXV (No. 3). - P.24-31. Safarova S.S. Bone reconstruction in type 1 diabetes // Bulletin of Siberian Medicine. - 2018. - Volume 17 (3). - P. 115-121. 14. Xiaoyan Chu, Kirgizova O.Yu., Mashanskaya A.V. O. Yu. Comparative analysis of different methods of treatment of metabolic syndrome and prediction of their effectiveness // New Medical Technology Bulletin. Electronic journal. - 2016.- No3.- P.57-62. 15. Udovichenko O.V., Grekova N.M. Diabetic foot. Handbook for Physicians. - M.: Applied Medicine, 2010.- 272 p. 16. Ulyanova I.N., Tokmakova A.Yu., Antsiferov M.B. Diagnosis of bone metabolism disorders in diabetic osteoarthropathy. Literature review // Osteoporosis and osteopathy. - 2001. - № 3. - P. 17. Ulyanova I.N., Tokmakova A.Yu., Yaroslavtseva M.V., Ilyin A.V., Galstyan G.R. Diabetic osteoarthropathy: modern treatments. // Diabetes mellitus. - 2010.- No 4.- P.70-73. 18. Abate M., Schiavone C., Pelotti P., Salini V. Limited joint mobility in diabetes and old age: recent advances in pathogenesis and therapy. // Int J Immunopathol Pharmacol. 2010. Vol.23 P.997-1003. 19. Bem R., Zhirkovska A., Fejfarová V., Skibova J., Yahudo E.B. Intranasal calcitonin in the treatment of acute Charcot neuroosteoarthropathy: a randomized controlled trial. // Treatment of diabetes. 2006. Vol.29 P.1392-1394. 20. Chia-Ying Yu, Fang-Ping Chen, Li-Wei Chen, Sheng-Fong Kuo, Rong-Nan Chien. The relationship between metabolic syndrome and bone fracture risk // .- 10p 21. Gokchen N., Altuntas S.C., Benlidayi I.C. Neglected rheumatic manifestations of diabetes mellitus: diabetic cheiroarthropathy. // Clin Rheumatol. - 2019. - Volume 38. - B.927-932. https://doi.org/10.1007/s10067-019-04454-z 22. Xinton P.S. The role of insulin in stimulating bone blood flow in the pathogenesis of metabolic insulin resistance and diabetic bone fragility. // Medical Hypotheses. - 2016.- Vol.93.- P.81–86. 23. Hockenbury R.T., Gruttadauria M., McKinney I. Use of implantable bone growth stimulation in Charcot ankle arthrodesis. // FootAnkle Int. - 2007. - Vol.28. - P.971-976.71-976. 24. Hopfner S, Krolak C, Kessler S, Tiling R. Preoperative imaging of Charcot neuroarthropathy. Does the additional use of 18F-FDG-Pet make sense? // Yadroviy medizin.- 2005. - 45-jild. - B.15-20. 25. Jeffcoate W.J., Game F.L. New theories on the causes of Charcot’s foot in diabetes. Diabetic Charcot on his feet: principles and management. Frykberg R. G., Ed. Brook Landville, MD, Data Trace Publishing Company, 2010.- P.29-44. 26. Jiao X., Xiao E., Graves D.T. Diabetes mellitus and its effect on the treatment of bones and fractures. // Curr Osteoporos Rep. - 2015. - Vol.13 (5) .- P.327-335. 27. Kannikar Vongdee, Narattaphol Charoenphandhu. Osteoporosis in diabetes mellitus: possible cellular and molecular mechanisms // World J Diabetes. - 2011. P.41-48. 28. Keidar Z., Militianu D., Melamed E., Bar-Shalom R., Israel O. Diabetic foot: a first experiment with 18F-FDG PEt / Ct. // J nucl Med. - 2005. - Volume 46. - B. 444-449. 29. Larkin M.E., Barni A., Braffett B.H. and others. Diabetes control and complication testing / Diabetes interventions and complication epidemiology research group (2014) Musculoskeletal system complications in type 1 diabetes. // Caring for diabetes. - 2014. - 37 vols. - P.1863-1869. https://doi.org/10.2337/dc13-2361 30. Liamis G., Liberopoulos E., Barkas F., Elisaf M. Diabetes mellitus and electrolyte disturbances. // World J Clin Cases. - 2014. - Vol.16; 2 (10) .- B. 488-496. 31. Molines L. et al. Charcot's foot: the latest findings in its pathophysiology, diagnosis and treatment. // Diabetes and metabolism. 2012. Vol.36 P.251-255. 32. Nakashima A., Yokoyama K., Yokoo T., Urashima M. The role of vitamin D in diabetes and chronic kidney disease. // Jahon J Diabetes. - 2016. - Vol.10; 7 (5) .- B.89-100. Pitocco D., Zelano G., Gioffrè G., et al. The association between osteoprotective G1181C and t245G polymorphisms and diabetic Charcot neuroarthropathy. // Caring for diabetes. - 2009. - Jil. 32 (9). - P.1694-1697. 33. Yamamoto M., Sugimoto T. End products of enhanced glycation, diabetes and bone strength. // Curr Osteoporos Rep. - 2016. - Vol.14 (6). - P.320–326.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.