Central Asian Journal of Medicine


The article provides information on methods of treatment of chronic rhinosinusitis in patients with chronic myelogenous leukemia and evaluation of its effectiveness. However, data on the use of subjective analog scale and endoscopic visual scale in assessing the severity of the disease and the effectiveness of treatment are presented. The object of the study was the clinic of the Republican Specialized Scientific and Practical Medical Center of Hematology (RSSPMCH), and 68 patients being treated there. When using complex treatment, the phenomenon of rhinosinusitis is observed in a significantly smaller number of patients - 1.2 times less often than in the comparison group. The duration of remission in the main group was 36 days longer than in the comparison group (p ˂ 0.05). The relapse rate decreased 2.4 times. The results obtained at the end of the course of treatment show that the treatment according to the recommended scheme helped to reduce the manifestation of symptoms of the inflammatory process and to significantly reduce the frequency of their occurrence. The results showed that the nasal cavity cleared of crusts faster and the amount of nasal discharge decreased.

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1. Ahn J.-C., Kim J.-W., Lee C.H., Rhee C.-S. Prevalence and Risk Factors of Chronic Rhinosinusitus, Allergic Rhinitis, and Nasal Septal Deviation. JAMA Otolaryngology–ead & Neck Surgery. 2016. Vol. 142. No 2. P. E1-E6. 2. Bachert C., Zhang L., Gevaert P. Current and future treatment options for adult chronic rhinosinusitis: Focus on nasal polyposis. Journal of Allergy and Clinical Immunology. 2015. Vol.136. No 6. P. 1431-1440. 3. Bhattacharyya N., Gilani S. Prevalence of Potential Adult Chronic Rhinosinusitis Symptoms in the United States. Otolaryngology–Head and Neck Surgery. 2018. Vol. 159. No 3. P. 522-525. 4. Bonnomet A, Luczka E, Coraux Ch, de Gabory L. Non–diluted seawater enhances nasal ciliary beat frequency and wound repair speed compared to diluted seawater and normal saline // Int Forum Allergy Rhinol. –2016. № 6 (10). Р. 1062–1068. https://doi.org/10.1002/alr.21782 5. Bulieva N.B. Epidemiology of opportunistic infections in hemoblastosis (review) // Medical Almanac –2011 September. –No. 5 (18). –p.132-137 6. Fokkens WJ., Lund VJ., Mullol J. Et al. European position paper on rhinosinusi– tis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology. – 2012. – Vol. 50. – № 1. – P.1–12. www.rhinologyjournal.com; www.EPOS.org. 7. Ghukasyan E.L. New opportunities for the diagnosis of rhinosinusitis. Abstract of the thesis. dis. ... Cand. honey. sciences. M., 2019.p.25 8. Hirsch A.G., Stewart W.F., Sundaresan A.S., Young A.J., Kennedy T.L., Greene S.J., FengW., Tan B.K., Schleimer R.P., Kern R.C., Lidder A., Schwartz B.S. Nasal and sinus symptoms and chronic rhinosinusitis in a population-based sample. Allergy. 2016. Vol. 72. No 2. P. 274-281. 9. Hoffmans R., Schermer T., Van Weel C., Fokkens W. Management of rhinosinusitis in Dutch general practice. Primary Care Respiratory Journal. 2011; 20 (1):64-70. 10. Hoffmans R., Wagemakers A., van Drunen C., Hellings P., Fokkens W. Acute and chronic rhinosinusitis and allergic rhinitis in relation to comorbidity, ethnicity and environment. PLoS One. 2018. Vol. 13. No. 2 P. e1- e14. 11. Ivanchenko O.A., Lopatin A.S. Chronic rhinosinusitis: epidemiology, classification, etiology, pathogenesis. Modern view of the problem // Bulletin of otorhinolaryngology. -2012. -№ 2. –p.91-96 12. Ivanchenko O.A., Lopatin A.S. Epidemiology of chronic rhinosinusitis: results of a multicenter survey of the adult population // Russian rhinology. 2013. T. 21. No. 3.p.16-19 13. Krivopalov A.A. Rhinosinusitis: classification, epidemiology, etiology and treatment // Medical Council No. 06, 2016. P.22-25. 14. Kryukov A.I., Tsarapkin G.Yu., Romanenko S.G., Tovmasyan A.S., Panasov S.A. Prevalence and structure of diseases of the nose and paranasal sinuses among the adult population of the metropolis // Russian rhinology. 2017.Vol. 25.No. 1. P.3-6. 15. Lopatin A.S. Treatment of chronic rhinosinusitis: in search of alternative methods // General Medicine 2018. №3. P.18-24. 16. Lopatin A.S. Chronic rhinosinusitis: pathogenesis, diagnosis and treatment principles. Clinical guidelines. Moscow: Practical Medicine, 2014. p. 3–61 17. Lopatin A.S., Ivanchenko O.A. Acute and chronic rhinosinusitis: new theories and previous questions // Medical Council. 2011. No. 9-10. P.52-57. 18. Lyamkina A.S., Pospelova T.I., Abitova M.Z. Chronic myeloid leukemia: current results of therapy in Novosibirsk // Actual problems of transfusiology and clinical medicine. –2015. -p. 298-300. 19. Shamkina P.A., Krivopalov A.A., Ryazantsev S.V. et al. Epidemiology of chronic rhinosinusitis // Modern problems of science and education. - 2019. - No. 3. http://www.science-education.ru/ru/article/view?id=28891 20. Turkina A.G., Golenkov A.K., Napso L.I. and other Russian register for the treatment of chronic myeloid leukemia in routine clinical practice: the results of many years of work // Effective pharmacotherapy. –2015. –No. 10 (1). -p. 8-13. 21. Yarmukhamedova N.F., Bakieva Sh.Kh., Salomova F.I. Epidemiology of diseases of the nose and paranasal sinuses with hemablastosis // Tibbiyotda yangi kun (2019), no. 1 (25/1) pp. 183-185.



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