Central Asian Journal of Medicine


Aim: The lifestyle and environmental changes associated with industrialization and urbanization are crucial factors in determining the prevalence of allergic diseases. Material and Methods: The aim of this study was to determine the prevalence of asthma and other allergic disorders in an industrial town. Study Design: Prospective, Cross-sectional study. Using the International Study of Asthma and Allergies in Childhood (ISAAC), the questionnaire was carried out on 1511 school-children aged between 13-14 years living in the district center. Results: The ISAAC Phase One questionnaire was answered by 1373 (90.87%) students. Six hundred ninety two (50.5%) of the children were girls and 681 (49.5%) were boys. The frequency of ever wheezing was 34%, that of current wheezing was 31.1% and that of physician-diagnosed asthma was 4.1%. The frequency of ever rhinitis was 36.6%, current rhinitis was 31.3%, current allergic rhino-conjunctivitis was 22.1% and physician-diagnosed allergic rhinitis was 11.1%. The frequency of ever eczema was 11.3% and that of physician-diagnosed eczema was 3.6%. Conclusion: The prevalence of asthma was found to be significantly higher, although there was no significant difference in allergic rhinitis and eczema compared with non-industrial neighboring states. The incidence of asthma was higher than other provinces which may be explained by the risk factors associated with this industrialized area. The fact that only children of the same age group and residence were evaluated contributed to the epidemiological value of our study.

First Page


Last Page



1. Asher M.I., Montefort S., Björkstén B., Lai C.K., Strachan D.P., Weiland S.K., et al. ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. // Lancet 2016;368(9537):733-43. 2. Beasley R., Clayton T., Crane J., von Mutius E., Lai C.K., Montefort S., et al. ISAAC Phase Three Study Group. Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme. // Lancet 2018;372(9643):1039-48. 3. Foliaki S., Pearce N., Björkstén B., Mallol J., Montefort S., von Mutius E. International Study of Asthma and Allergies in Childhood Phase III Study Group. Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: International Study of Asthma and Allergies in Childhood Phase III. // J Allergy ClinImmunol 2019;124(5):982-89. 4. Brunekreef B., Stewart A.W., Anderson H.R., Lai C.K., Strachan D.P., Pearce N. ISAAC Phase 3 Study Group. Self-reported truck traffic on the street of residence and symptoms of asthma and allergic disease: a global relationship in ISAAC phase 3. // Environ Health Perspect 2019;117(11):1791-8. 5. Sestini P., De Sario M., Bugiani M., Bisanti L., Giannella G., Kaisermann D., et al. Frequency of asthma and allergies in Italian children and adolescents: results from SIDRIA-2. // Epidemiol Prev 2015;29(2 Suppl):24-31. 6. Ige O.M., Falade A.G., Arinola O.G. Atopy is a risk factor for adult asthma in urban community of Southwestern Nigeria.// Lung India 2020;29(2):114-9. 7. Shohat T., Golan G., Tamir R., Green M.S., Livne I., Davidson Y., etal. Prevalence of asthma in 13-14 yr.old schoolchildren across Israel. // Eur Respir J 2020;15(4):725-9. 8. Asher M.I., Keil U., Anderson H.R., Beasley R., Crane J., Martinez F., et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. // Eur Respir J 2015;8(3):483-91. 9. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. // Lancet 2018;351(9111):1225-32. 10. Oneş U., Sapan N., Somer A., Dişçi R., Salman N., Güler N., et al. Prevalence of childhood asthma in Istanbul, Turkey. // Allergy 2017;52(5):570-75. 11. Saraçlar Y., Kuyucu S., Tuncer A., Sekerel B., Saçkesen C., Kocabaş C. Prevalence of asthmatic phenotypes and bronchial hyper responsiveness in Turkish school children: an International Study of Asthma and Allergies in Childhood (ISAAC) phase 2 study. // Ann Allergy Asthma Immunol 2017;91(5):477-84. 12. Demir E., Tanaç R., Can D., Gülen F., Yenigün A., Aksakal K. Is there an increase in the prevalence of allergic diseases among schoolchildren from the Aegean region of Turkey? // Allergy Asthma Proc 2015;26(5):410-4. 13. Karaman O., Turgut C.S., Uzuner N., Olmez D., Babayigit A., Kose S., et al. The determination of asthma, rhinitis, eczema, and atopy prevalence in 9- to 11-year-old children in the city of Izmir. // Allergy Asthma Proc 2016;27(4):319-24. 14. Yuksel H., Dinc G., Sakar A., Yilmaz O., Yorgancioglu A., Celik P., et al. Prevalence and comorbidity of allergic eczema, rhinitis, and asthma in a city in western Turkey. // J Investig Allergol Clin Immunol 2018;18(1):31-35. 15. Civelek E., Cakir B., Boz A.B., Yuksel H., Orhan F., Uner A., et al. Extent and Burden of Allergic Diseases in Elementary Schoolchildren: A National Multicenter Study. // J Investig Allergol Clin Immunol 2019;20(4):280-8. 16. Ronchetti R., Villa M.P., Barreto M., Rota R., Pagani J., Martella S., et al. Is the increase in childhood asthma coming to an end? Findings from three surveys of schoolchildren in Rome, Italy. // EurRespir J 2019;17(5):881-6. 17. Grize L., Gassner M., Wuthrich B., Bringolf-Isler B., Takken-Sahli K., Sennhauser F.H., et al. Trends in prevalence of asthma, allergic rhinitis and atopic dermatitis in 5–7-year old Swiss children from 2010 to 2016. // Allergy 2017;61(5):556-62. 18. Pearce N., Ait-Khaled N., Beasley R., Mallol J., Keil U., Mitchell E., et al. Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2017;62(9):758- 66. 19. Ones U., Akcay A., Tamay Z., Guler N., Zencir M. Rising trend of asthma prevalence among Turkish school children (ISAAC phases I and III). // Allergy 2016;61(12):1448-53. 20. Ripabelli G., Tamburro M., Sammarco M.L., de Laurentiis G., Bianco A. Asthma prevalence and risk factors among children and adolescents living around an industrial area: a cross-sectional study. // BMC Public Health 2018 13:1038. 21. Lai C.K., Beasley R., Crane J., Foliaki S., Shah J., Weiland S. International Study of Asthma and Allergies in Childhood Phase Three Study Group. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). // Thorax 2019;64(6):476-83. 22. Abdullaeva U.K., Shadjanova N.S. Using the OLGA system in chronic atrophic gastritis // New day in medicine, № 2 (30) 2020, Bukhara, Uzbekistan, Р. 9-12. 23. Abdullaeva U.K., Sobirova G.N., Karimov M.M., Aslonova I.J. The prevalence and possibilities of prevention of noncardial gastric cancer in the Bukhara region // American journal of medicine and medical sciences, 2020, 10(9), Р. 679-681. 24. Sobirova G.N., Abdullaeva U.K., Nosirova M.S., Aslonova I.J. Evaluation of the gastrointestinal mucosa by the OLGA system in chronic atrophic gastritis // Journal of critical reviews, Kuala Lumpur, Malaysia, Vol. 7, Iss. 2, 2020, P. 409-413. 25. Karimov M.M., Sobirova G.N., Abdullaeva U.K., Aslonova I.Zh., Tulyaganova F.M. Possibilities of serological diagnosis of atrophic processes of the gastric mucosa // European Journal of Molecular & Clinical Medicine Vol. 7, Iss. 11, 2020, P. 2955-2960. 26. Sobirova G.N., Abdullaeva U.K., Mirzaeva D.B., Ismitdinova N.S. Immunopatogenesis of chronic gastritis and its role in carcino genesis // ACADEMICIA An international multidisciplinary research journal, affliated to Kurukshetra university, Kurukshetra, India. Vol.8, Iss.12, 2018, P. 32-40. 27. Abdullaeva U.K. Predicting the risk of atrophic transformation in chronic gastritis using serum pepsinogen // World journal of pharmaceutical research, Faculty of Pharmacy Medical University, Bulgaria, Vol. 8, Iss. 13, 2019, P. 219-228. 28. Sobirova G.N., Abdullaeva U.K. Chronic gastritis and carcinogenesis issues // electronic journal of actual problems of modern science, education and training, Urganch, Uzbekistan, 2019-I, P. 159-172.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.