Central Asian Journal of Medicine


Background. The incidence of coronary artery disease (CAD) varies depending on age, gender and ethnicity, but the precise differences remain to be firmly established. This study therefore evaluated the disparity in coronary artery calcification (CAC), as a marker of CAD, in adults of Uzbekistan. Materials and Methods. A total of 1541 patients were involved in our study, including 1093 (70.9%) males, with an average age of 52.4 ±10.6 years, and 448 (29.1%) females, with an average age of 57.5 ±9.9 years. Persons of Asian nationalities prevailed - 1356 (88%), Europeans accounted for 185 patients (12%). The study was carried out on the multidetector spiral CT scanners “Brilliance 64” and “Brilliance i-CT 256” (PHILIPS). Results. The majority patients (n=787, 51.1%) had a zero coronary artery calcium scoring (CACS). 378 (24.5%) patients had low CAC rates (1–100). Moderate CAC rates (100-400) were observed in 211 cases (13.7%). Patients with CACS> 400 found the smallest number (n = 165, 10.7%). Zero CACS level was more common (92.3%) in the age group under 40 years. CAC and prevalence steadily rose with the increasing age. Patients within the age groups of 50–59 years and 60–69 years dominating the non-zero CACS population (n = 278, 36.9% and n = 290, 38.5%, respectively). Asian males were found to have lower calcium levels compared to European males (non-zero CACS 51.1% and 62.3% respectively), and the same trend was observed in Asian and European women (non-zero CACS in 32.5% and 44.4% respectively). Conclusion. Findings from this study showed that the distribution of CAC was markedly affected by the age, sex and race of our studied population. CAC increases with age in both men and women. The prevalence and severity of coronary atherosclerosis appeared lower in Asian population compared with Europeans.

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