Central Asian Journal of Medicine


This article provides data on the clinical and functional rationale for the use of Ganoderma Lutsidum in the treatment of chronic catarrhal gingivitis in children. It is known that due to the widespread, insufficiently accurate clinical and instrumental diagnosis and treatment tactics, this disease leads to the loss of a significant part of the teeth already at a young age, the presence of foci of chronic infection, impaired function of the masticatory-speech apparatus, which allows us to consider this pathology not only a serious medical, but also an important social problem. This article used a complex of clinical and functional research methods, in which, in addition to traditional methods, laser Doppler flowmetry was used. The presented results indicate a high therapeutic activity of the Ganoderma Lucidum, which is proved by a complex of clinical and functional studies. The corresponding conclusions are made, practical recommendations are offered.

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1. Aromatic constituents from Ganoderma lucidum and their neuroprotective and anti-inflammatory activities / Shuang-Yang Li et at. // Fitoterapia, htpps: // doi.org./10.1016/j.fitote.2019.01.013 2. Bioactive metabolites of Ganoderma Lucidum: Factors, mechanism and broad spectrum therapeutic potential / Chetan Sharma et at. // Journal of Herbal Medicine, https: //doi.org/10.1016/j.hermed.2019.10.002 3. Characterization, hypolipidemic and antioxidant activities of degraded polysaccharides from Ganoderma Lucidum / Yu Xu et at. // International Journal of Biological Macromolecules, htpps: //doi.org/10.1016/j.ijbiomac.2019.05.166 4. Comparison on characterization and antioxidant activity of polysaccharides from Ganoderma lucidum by ultrasound and conventional extraction / Qiaozhen Kang et at. // International Journal of Biological Macromolecules, htpps: //doi.org/10.1016/j.ijbiomac.2018.11.215 5. Dayaolingzhiols A-E, AchE inhibitory meroterpenoids from Ganoderma lucidum / Qi Luo et at. // Tetrahedron, htpps: //doi.org/10.1016/j.tet.2019.04.022 6. Development of Ganoderma lucidum spore powder based proteoglycan and its application in hyperglycemic, antitumor and antioxidant function / Li-Fang Zhu et at. // Process Biochemistry, htpps: //doi.org/10.1016/j.procbio.2019.05.025 7. DNA damaging potential of Ganoderma lucidum extracts / Maria Soledad Vela Gurovic et at. // Journal of Ethnopharmacology, htpps://doi.org/10.1016/j.jep.2018.02.005 8. Effects of deproteinization methods on primary structure and antioxidant activity of Ganoderma lucidum polysaccharides / Xiaotong Zeng et at. // International journal of Biological Macromolecules, htpps://doi.org/10.1016/j/ijbiomac.2018.12.222 9. Encapsulation efficiency and controlled release of Ganoderma lucidum polysaccharide microcapsules by spray drying using different combinations of wall materials / Ping Shao et at. // International Journal of Biological Macromolecules, htpps://doi.org/10.1016/j.ijbiomac.2018.12.153 10. Engineering of Ganoderma lucidum polysaccharide loaded polyvinyl alcohol nanofibers for biopharmaceutical delivery / Li-Fang Zhu et at. // Journal of Drug Delivery Science and Technology, htpps://doi.org/10.1016/j.jddst.2019.01.032 11. Extraction and isolation of ganoderic acid R from Ganoderma lucidum / Chihiro Murata et at. // Tetrahedron Letters, htpps://dx.doi.org/10.1016/j.tetlet.2016.10.072 12. Hypoglycemic effect of inulin combined with ganoderma lucidum polysaccharides in T2DM rats / Yaping Liu et at. // Journal of Functional Foods, htpps://doi.org/10.1016/j.jff.2019.02.036 13. Hypolipidaemic and anti-lipidperoxidant activities of Ganoderma lucidum polysaccharide / Shengjun Wu // International Journal of Biological Macromolecules, htpps://doi.org/10.1016/j.ijbiomac.2018.07.082 14. Microcapsulation of Ganoderma Lucidum spores oil: Evaluation of its fatty acids composition and enhancement of oxidative stability / Dan Zhou et at. // Imdustrial Crops&Products, htpps://doi.org/10.1016/j.indcrop.2019.01.031 15. Polysaccharide peptides from Ganoderma lucidum ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet-fed rats / Xu-Cong Lv et at. // Journal of Functional Foods, htpps://doi.org/10.1016/j.jff.2019.03.043



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