Central Asian Journal of Medicine


Objective: To study the clinical, neurological and diagnostic aspects of headaches in congenital pre-cerebral angiodysplasia. Materials and Methods: There were 213 patients with headaches under our supervision. The core of the studied cohort was migraine patients, which amounted to 179 (100%) cases, among them migraine with angiodysplasia- (MWA) was 136 (45.9%), followed by patients with migraine without angiodysplasia (MWOA) – 43 (14.5%), tension headache (TH) – 26 (8.8%), cluster headache (CH) – 8 (2.7%) patients. The study used clinical neurological, neuropsychological, neuroimaging and statistical methods. Results: Migraine can develop in people with congenital pre-cerebral angiodysplasia in 76% of cases, and in people without congenital abnormalities of cerebral vessels – 24%. At the same time, patients with congenital pre-cerebral angiodysplasias most often develop migraine with aura in 62.5% of cases, whereas without it its simple form is 88.4%. Indicators of the scale of VAS, MIDAS and HALT index were the highest in the group of patients with combined angiodysplasias, amounting to 9.02±0.09:20.9±0.2 and 21.1±0.2 points, the lowest with isolated hypo/aplasias and pathological PA deformations 6.5±0.04:15.5±0.1: 16.5±0.1 and 6.6±0.04:15.5±0.1:16.5±0.1, respectively. Conclusions: Congenital precerebral angiodysplasia can lead to the development of migraine, most often migraine with aura, while they have a high intensity headache, with a decrease in the daily activity of patients and the need for medical care.

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