Central Asian Journal of Medicine


The purpose of literature review is analytical analysis of the prevalence of ischemic heart disease in the patients with COPD. In this article there is noted significance of the subject area. There are presented detailed data about possible causes for development of this comorbid state, described literature data about possible common pathogenic mechanisms and risk factors. It is emphasized that cardiovascular risk increasing in the patients with COPD, with elevation of severity of disease, growing of the exacerbation frequency. In the rather complete volume there are presented information about role of endothelial dysfunction, chronic systemic inflammation and the system of coagulation and anticoagulation as common pathogenic mechanisms providing development of myocardial infarction in the patients with COPD in this article.

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