Central Asian Journal of Medicine


Objective: To estimate the microscopic, sub-microscopic and morphometric changes of the myocardium of theheart wall during early postnatal ontogenesis under the influence of pesticides which have passed through the mother’s milk. Materials and methods: The material for the experiment served as the slides of rat myocardium 205 different period of early postnatal ontogenesis. Results: Studies have shown that, when exposed manager that kinmiks thickness and atrial and ventricular walls at all ages is reduced as compared with the control group. The change depends on the type of pesticide, rat age and heart. Conclusion: When exposed to pesticides in the myocardium of the heart observed pathological changes indicative of developing toxic myocarditis.

First Page


Last Page



1. Kasymov A. KH., Khakberdiyev M. M., Gutnikova A. R., Kosnikova I. V., Tukhtamuradov Z. Z., Gutnikova L. V. // Toksikol. vestn. – 2000. – №5. – S. 32-35. 2. Lavrent'yev I. Ye., Mishina T. N. Vliyaniye pestitsidov i metallov peremennoy valentnosti na vyrazhennost' okislitel'nogo stressa u zhivotnykh // Byul. med. Internet-konf. – 2012. – Tom 2, №11. – S. 845. 3. Mirsharapov U. M., Akhmedova S. M. Morfologicheskiye osobennosti voloknistykh struktur stenki predserdiy i zheludochkov serdtsa krysy // Vestnik Tashkentskoy meditsinskoy akademii. – Tashkent, 2015. - № 2. - S. 46-49. 4. Khamrokˌ ulova M.A. Klinicheskiye proyavleniya u bol'nykh s khronicheskoy intoksikatsiyey pestitsidami, lecheniye putem korrektsii metabolicheskikh narusheniy // Teoreticheskoy i klinicheskoy meditsiny.– 2014. -№1 S. 67-70. 5. Tsyrempilov P. B., Konstantinova S. A. Vozdeystviye pestitsidov na biosintez belka, sostoyaniye lizosomal'nykh membran i effektivnost' immunizatsii zhivotnykh // Byul. Vost.-Sibirskogo NTS SO RAMN. – 2009. –№2 (66). – S. 109-112. 6. Akhmedova S.M. Histological structure of rat heart in the early stages of ontogeny //European science review, Austria, Vienna, 2016. - № 5–6. - Р. 30-33. 7. Calvert G., Rodriguez L., Prado J. Worker illness related to newly marketed pesticides--Douglas County, Washington, 2014. // MMWR Morb Mortal Wkly Rep. – 2015. – Vol. 64, №2. – Р. 42-44. 8. Chan Y. C., Chang S. C., Hsuan S. L., Chien M. S., Lee W. C., Kang J. J., Wang S. C., Xiao J. W. Cardiovascular effects of herbicides and formulated adjuvants on isolated rat aorta and heart. Department of Food and Nutrition, Providence University, Taichung 433, Taiwan, ROC. // Toxicol In Vitro. – 2007. -№2. – Р. 142-144.



To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.