Central Asian Journal of Medicine


Analysis of clinical, biochemical and neurophysiological features of Duchenne and Becker progressive muscular dystrophy in patients with neuromuscular diseases. Materials and Methods: A prospective and retrospective studies of 310 children with pseudohypertrophic forms of progressive Duchenne’s (PDMD) and Becker’s (PBMD) muscular dystrophies were conducted. Results: In children with PDMD deformation of the skeleton, impaired movement and the inability to stand up independently were noted almost 3 times more often than in children with PBMD. EMG for PDMD was characterized by a large number of low-amplitude potentials of fibrillation than for PBMD. Conclusions: PBMD is characterized by a slower course and later onset than Duchenne’s, but both forms have similar clinical signs. The results of needle EMG reflect the nature and severity of the process, help to assess the quality of life and predict the course of the disease.

First Page


Last Page



1. Ginter E.K. Ginter E K., Zinchenko R.A. Nasledstvennye bolezni v Rossiyskix populyatsiya // Vestn. VOGiS. - 2006. - T. 10, №1. - S. 106-125. 2. Dadali E.L., Podagova E.V., Malmberg SA, Kuznetsov А.А. Algorithm diagnostic psevdogipertroficheskix progressiruyushchix myshechnyx dystrophy // Nervnye bolezni. - 2007. - №2. - S. 9-12. 3. Andrews J.G., Davis M.F., Meaney F.J. Correlates of care for young men with Duchenne and Becker muscular dystrophy // Muscle Nerve. – 2013. – Vol 5. – Р. 4-11. 4. Dorobek M., Szmidt-Sałkowska E., Rowińska-Marcińska K. et al. Relationships between clinical data and quantitative EMG findings in facioscapulohumeral muscular dystrophy // Neurol. Neurochir. Pol. – 2013. – Vol. 47, №1. –Р. 18-17.