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Scientific Journal of Samarkand University

Abstract

The chromatographic retention of the derivatives of pyrimidinone and isoquinolinewas studied under conditions of reversed-phase variant of HPLC. The retention factors were determined for various eluent compositions (CH3CN, CH3OH, and H2O). The relationship between the structure, properties and chromatographic retention of isoquinoline derivatives has been investigated

First Page

72

Last Page

76

References

1. Shaxidoyatov X.M. , Xadjiniyazov X.U. Funksionalno-zameshyonnie pirimidini. – Tashkent, 2012. – S.251-266 2. Kaliszan R. Quantitative Structure-Chromatographic Retention Relationships. N.Y.:Wiley, 1987. 303 r. 3. Nametkin S.S. Geterotsiklicheskiye soyedineniya. M.: Nauka, 1981. S.259-263 4. Shats V.D., Sahartova O.V. Visokoeffektivnaya jidkostnaya xromatografiya. Riga: Zinatne. 1988. 390s. 5. Snyder L.R., Poope H. // J. Chromatogr. 1980. V. 184. P. 363-413. 6. Horvath Cs., Melander W., Molnar J. // Anal.Chem. 1977. V. 49. №1. P. 142-154.

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