Central Asian Journal of Pediatrics

Central Asian Journal of Pediatrics


Background. Preeclampsia is the most serious pregnancy complication that poses a threat of the mother’s and baby’s life. In almost all cases, due to a disorder of the function of vital organs - the brain, liver, lungs, kidneys - multiple organ failure develops and progresses. Adaptation of newborns in the early neonatal period depends on the functions of the mother-fetus system. We aimed to to study the features of the period of early adaptation in preterm infants born to women with preeclampsia. Methods. The study involved 40 preterm infants who were divided into 2 groups: of which 20 preterm infants born to mothers with preeclampsia (group I - main) and 20 full-term babies from mothers without preeclampsia (group II - comparative) born in the same period. Obstetric history of mothers, examined newborns, Apgar score, clinical - laboratory and instrumental studies were examined. Results.The parity of childbirth in the group of women with preeclampsia was 2.25 ± 0.8 and 1.7 ± 0.53 in the control group. Among the identified complications of pregnancy in women with preeclampsia, FPF is at the first place in 80% (n = 16) of mothers, at the second - anemia 70% (n = 14), at the third - the threat of termination in 55% (n = 11) of women, fourth - gestosis in 35% (n = 7), SARS 25% (n = 5) were detected to a lesser extent. Conclusion.High risk factors for the development of perinatal pathology and maladaptation syndrome in premature infants are the presence of a burdened obstetric history in women, as well as preeclampsia, fetoplacental insufficiency, and birth asphyxiation.

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