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Central Asian Journal of Pediatrics

Central Asian Journal of Pediatrics

Abstract

Chronic obstructive pulmonary disease (COPD) is a socially significant disease. The study studied the spontaneous and induced enhancement of cytokines IL-4, IL-6, IL-8, IL-10 by blood leukocytes in patients with chronic obstructive pulmonary disease. It has been shown that the leading role in the formation of the inflammatory process in COPD belongs to the cytokines IL-6, IL-8. Cytokine production mainly reflects the reserve capacity of immunocompetent cells in response to pathogenic factors.

First Page

24

Last Page

29

References

1. Abdurakhmanova I.S., Nikulicheva V.I., Vagapova D.R., Yenikeyev O.A. Kharakter ekspressii provospalitel'nykh tsitokinov u bol'nykh khronicheskoy obstruktivnoy bolezn'yu legkikh // Saratovskiy nauchno-meditsinskiy zhurnal, 2010. T. 6, № 2. S. 314-317. [Abdurakhmanova I.S., Nikulicheva V.I., Vagapova D.R., Enikeyev O.A. Proinflammatory cytokine expression in patients with chronic obstructive pulmonary disease. Saratovskiy nauchno-meditsinskiy zhurnal = Saratov Journal of Medical Scientific Research, 2010, Vol. 6, no. 2, pp. 314-317. (In Russ.)] 2. Aralov N. R. i dr. Diagnosticheskaya znachimost' IL-8 I IL-12 pri razlichnykh formakh interstitsial'noy bolezni legkikh //vestnik vracha. – s. 14. 3. Berezhnaya N.M. Tsitokinovaya regulyatsiya pri patologii: stremitel'noye razvitiye i neizbezhnyye voprosy // Tsitokiny i vospaleniye, 2007. T. 6, № 2. S. 26-34. [Berezhnaya N.M. Cytokine regulation in pathology: rapid development and inevitable questions. Tsitokiny i vospalenie = Cytokines and Inflammation, 2007, Vol. 6, no. 2, pp. 26-34. (In Russ.)] 4. Fiseselmann J.F., Richerson H.B: Respiratory diseases // Basic and Clinical Immunology. — 8th ed. / Ed. by D.P. Stites, Al. Terr, T.G. Parslow. — Norwalk, CT: Appleton & Lange, 2014. — P. 528-540.

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