Scientific Bulletin of Namangan State University


the respiratory and phosphorylating activity of mitochondria of brown fat of guinea pigs during the oxidation of various substrates was studied. It was shown that pyruvate + malate is oxidized, is associated with the synthesis of ATP, but has high respiration V4; with succinate oxidation, a higher level of V4 is observed. The oxidation of NADH occurs in a completely non-conjugated way, since the oxidation process does not respond to the addition of ADP or uncoupling. The data obtained indicate the functioning of intensive non-conjugated respiration in the mitochondria of this tissue. It is able to convert respiration energy into heat, since the main function of brown fat is heat production.

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