"ON THE POSSIBILITY OF UNCOUPLED MITOCHONDRIA IN BROWN FAT OF NEWBORN " by Rashid Nasipovich Axmerov, Mirzohid Mirzavaliyevich Mirzaolimov et al.

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Scientific Bulletin of Namangan State University

Article Title

ON THE POSSIBILITY OF UNCOUPLED MITOCHONDRIA IN BROWN FAT OF NEWBORN GUINEA PIGS

Authors

Rashid Nasipovich Axmerov, Namangan State University, Namangan
Mirzohid Mirzavaliyevich Mirzaolimov, Namangan State University, Namangan
Bahodir Allaberganovich Niyazmetov, Namangan State University, Namangan
Akmaljon Usmonjonovich Najimov, Namangan State University, Namangan

Abstract

the respiratory and phosphorylating activity of mitochondria of brown fat of guinea pigs during the oxidation of various substrates was studied. It was shown that pyruvate + malate is oxidized, is associated with the synthesis of ATP, but has high respiration V4; with succinate oxidation, a higher level of V4 is observed. The oxidation of NADH occurs in a completely non-conjugated way, since the oxidation process does not respond to the addition of ADP or uncoupling. The data obtained indicate the functioning of intensive non-conjugated respiration in the mitochondria of this tissue. It is able to convert respiration energy into heat, since the main function of brown fat is heat production.

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References

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Recommended Citation

Axmerov, Rashid Nasipovich; Mirzaolimov, Mirzohid Mirzavaliyevich; Niyazmetov, Bahodir Allaberganovich; and Najimov, Akmaljon Usmonjonovich (2019) "ON THE POSSIBILITY OF UNCOUPLED MITOCHONDRIA IN BROWN FAT OF NEWBORN GUINEA PIGS," Scientific Bulletin of Namangan State University: Vol. 1 : Iss. 9 , Article 10.
Available at: https://uzjournals.edu.uz/namdu/vol1/iss9/10

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