Scientific Bulletin of Namangan State University


The article states that o-cresols react with chloroacetyl chloride under different conditions. This reaction with the FeCl3 catalyst at 130-140 ° C at a ratio of 1: 1 to 1.5.10-3 was 81% high. Decrease in the amount of catalyst has led to an increase in product quality. In these conditions, isomeric matter formation was confirmed by thin layer and gas chromatography.

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1. Cullinane N.M., Edwards F.R. Comparison of the Fries and Friedel-Crafts reactions J.Appl. Chem. -1959. -Vol. 9. -P.133-136. 2. Fries K., Fink G. uber Homologe des cumarons und itheabkemmlinge // Ber. 1908. B. 41. S. 4271-4284. Bekker G. Vvedenie v elektronnuyu teoriyu organicheskix reaksiy. Moskva: Mir., 1965. - 631 s



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