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Karakalpak Scientific Journal

Abstract

It is well known that the plant of lacrisa (Russian salodka, Uzbek buyan (or kizilmiya)), which is widely spread in the Middle Asia region, is dominated by biological activity against infectious (influenza, herpes, hepatitis, chlamydia) diseases. It is determined that glycyrizic acid is responsible for this biological activity, which is included in the constituent part of licorice (especially in its roots). It has been studied that glycyrrhizic acid with other preparations, for example with Megosin, has a supramolecular complex, a new preparation of Megoferon, which induces interferon biosynthesis several times more (5120 units/ml) than Megosin itself.

First Page

29

Last Page

33

DOI

ISSN 2181-9203

References

1. Dudchenko LG, Koziakov AS, Krivenko VV Spicy-aromatic and spicy-taste plants: Reference book / Ans. Ed. K.M. Sytnik. - K .: Naukova dumka, 1989. - 304 p. - 100 000 copies. - ISBN 5-12-000483-0. 2. Licoric.: Medline Plus Supplements, United States National Library of Medicine, National Institutes of Health. 2011. 3. Arase, Yasuji; Ikeda, Kenji; Murashima, Naoya; Chayama, Kazuaki; Tsubota, Akihito; Koida, Isao; Suzuki, Yoshiyuki; Saitoh, Satoshi; Kobayashi, Masahiro; Kumada, Hiromitsu (15 April 1997). "The long term efficacy of glycyrrhizin in chronic hepatitis C patients". Cancer. 79 (8): 1494–1500. doi:10.1002/(SICI)10970142(19970415)79:8<1494::AID-CNCR8>3.0.CO;2-B. 4. Van Rossum, TG; Vulto, AG; Hop, WC; Schalm, SW (December 1999). "Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection". Clinical Therapeutics. 21 (12): 2080–90. doi:10.1016/S0149-2918(00)87239-2. PMID 10645755. 5. Namozov O.M. Dissertational work on the theme of "Methods of regulation for of biosynthesis endogenous interferon".

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