•  
  •  
 

Problems and perspectives in pharmaceutics and drug discovery

Abstract

As a result, it was found that the preparation «Gepafors» is bioidentical of the acute toxicity of the preparation «Legalon», as well as both preparations when administered orally with a maximum dose do not cause the death of animals (LD50>3075 mg/kg). A study of the hepatoprotective activity of the preparations showed that both preparations have a statistically significant hepatoprotective effect and are bioequivalent of hepatoprotective activity

First Page

80

Last Page

85

References

1. Minushkin O.N. Gepatoprotektori v lechenii nekotorix zabolevaniy pecheni// Meditsinskiy sovet. - 2016. - 14. - S. 52-57.2. Rukovodstvo po eksperimentalnomu (doklinicheskomu) izucheniyu novix farmakologicheskix veshestv / [pod obsh. red. R. U. Xabrieva]. - 2-e izd., pererab. i dop. - M.: OAO "Izd-vo "Meditsina", 2005. - 832 s.3. Rukovodstvo po provedeniyu doklinicheskix issledovaniy lekarstvennix sredstv. Chast pervaya / [pod red. A.N. Mironova]. - M.: Grif i K, 2012. - 944 s.

Share

COinS