Problems and Perspectives in Pharmaceutics and Drug Discovery
Article Title
Abstract
New derivative colchicines К-26 has shown higher antineoplastic activity on animals with stain the Sarcoma 180 in comparison with taxol and etoposide, and smaller quantity of by-effects at application in a therapeutic dose that assumes its further profound studying on others tumors strains, and also in other modes of application.
First Page
98
Last Page
101
References
1. BalitskhK.P., Voronina A.A. Lekarsrvennue rasteniya vterapii zlokachestvenmix opuxoley. Izd-vo Rostovskogo univ., 1976, s.66-136. 2. Yenikeyeva Z.M. Kuznetsova H. H, Dimantl H , BegishevaA. I, Sultatiova D.Sh. 10-dezmetoksi-10-(N,N- bis (2-gidroksietil)amino)-7-(N-dezatsetil) kobcitsin, obladayushiy tsitostaticheskim deystviyem na kletkipodjeludochnoy jelezi cheloveka i antimiroricheskim effektom. Patent [UZCJ 951,2003 3. Yenikeye\ a Z.M., Ibragimov A.A. Novuy klass tsitostatikov so srimufyarsiyey koloniyeobrazuymixyedinits na selezetike (KOYEs). Tashkent, iz-vo "Fanvatextiologiya", 173s 4. Metodicheskiye ukazaniyapo izucheniyuprorivoopuxolevoy akrhmostifarmakologicheskix veiestv. Sostaviteli Ye.M.Treiiaina, O.S.Jukova, G.KGerasimova, N.VAndronova, A.M.Garin v kn. "Rukovodstvopo eksperimentalnomu (doklinicheskomu) izucheniyu novtvfarmakologicheskix veiiestv". Podobiiey red. R.UJCabrtyeva. \losk\a, 2005, s.637-682. 5. CidowvKK Toksikologiya no\nixpromusiilenmix ximicheskix veiiestv - M.: Meditsina, 1973, vxip.3, -47s 6. Usmanov RX, Raxmatullayeva D.T., Yenikeyeva Z.M. Razrabotka sxemphmeneniya novogo otechestvennogoprorivoopuxolevogo preparata dekotsinpri lechetiii raka koji vekipehorbitalnoy oblasti. "Med.j.Uzbekistana", 2011 g. 6, s.37-39\ 7. Bombardelli E. Colchicine-skeleton Compounds. Their Use as Medicaments and Compositions Containing Them. // US Pat. 6.080.739. 2000. 8. Bombardelli E.. Gabetta B. Colchicine Derivatives and the Therapeutically //Use Thereof. US Pat. 5.843.910, 1998. 9. Holikov T.K.. Gufur-Akhunov М.Л., GoyibovaS. YenikeevaZ.M.« Newantitumourpreparation- decocini-forthetreatmen-tofskincancer. andigreaslngeffectofirradiationtothetumouraswelh.JournalAvicena- Friburg - Germany. Heft 2. 2011. s. 32-37 10. Qian Shi. Ke Chen. Susan L. Morris-Natschke and Kuo-Hsiung Lee. Recent Progress in the Development of Tubulin Inhibitors As Antimitotic Antitumor Agents. //Current-Pharmaceutical Design.. 1998. No 4. P. 219-248. 11. RiodelJ.. Jatrot Si.. Picot M.. Berieel H.. et. al. Therapeutic response to taxol of six human tumors xe nografted into nude mice.//Cancer Che mother a. And Pharmacol., 1986. V 17. №2. P.137-142.
Recommended Citation
Enikeeva, Z.M; Agzamova, N.A.; and Abdirova, A.C
(2018)
"Comparison activity of new antineoplastic preparation к-26 with taxol and etoposide on strain the sarcoma 180 abstract,"
Problems and Perspectives in Pharmaceutics and Drug Discovery: Vol. 3
:
Iss.
1
, Article 21.
Available at:
https://uzjournals.edu.uz/farjur/vol3/iss1/21