The aim of this work is to study the reaction of 2-methyl-5-ethynylpyridine N-oxide with some aliphatic and aromatic amines to obtain N-oxides of pyridylacetylenic amines. 2-Methyl-5-ethylpyridine converted to 2-methyl-5-vinylpyridine by dehydrogenation, and 2-methyl-5-ethynylpyridine obtained by bromination and dehydrobromination. 2-methyl-5-ethynylpyridine N-oxide synthesized by oxidation of 2-methyl-5-ethynylpyridine with perhydrol in acetic anhydride. The synthesis of N-oxides of pyridylacetylenic amines by the Mannich reaction carried out. The effect of the solvents: methanol, ethanol and n-dioxane, the catalyst, and the reaction time on the yield of the final product studied. The structure and composition of the synthesized PAA N-oxides were established using IR and PMR spectroscopy.
IKRAMOV, Abduvakhab; ZIYADULLAYEV, Odiljon; KHAMIDJANOV, Adkham; BOJARIEV, Shavkat; and KHANDAMOV, Davron
"SYNTHESIS OF SOME N-OXIDES OF PYRIDYLACETHYLENE AMINES BASED ON 2-METHYL-5-ETHYNYLPYRIDINE,"
CHEMISTRY AND CHEMICAL ENGINEERING: Vol. 2021
, Article 9.
Available at: https://uzjournals.edu.uz/cce/vol2021/iss1/9