The aim of the study is to develop a technology for obtaining a food additive for the extract of the pulp of bitter watermelon - Citrullus colocynthis, introduced in Uzbekistan as a hypoglycemic agent. Pharmacological studies have shown the presence of a hypoglycemic effect for aqueous and alcoholic extracts and 2-O-β-glucopyranosyl-cucurbitacin E in rats with alloxan diabetes mellitus. Cucurbitacins were isolated from the extract - cucurbitacin E, 2-O-β-glucopyranosyl-cucurbitacin E and other bioactive substances.
The food supplement obtained from bitter watermelon (Citrullus colocynthis (family Cucurbitaceae)) according to the developed technology showed a higher hypoglycemic activity compared to the drug arfazetin.
BOBAEV, Isomiddin; MAKHMUDOVA, Маrkhаbоkhон; BOBAKULOV, Khayrulla; SYROV, Vladimir; and ABDULLAEV, Nasrulla
"TECHNOLOGY OF OBTAINING A FOOD ADDITIVE FROM CITRULLUS COLOCYNTHIS AND ITS HYPOGLYCEMIC ACTIVITY,"
CHEMISTRY AND CHEMICAL ENGINEERING: Vol. 2021
, Article 13.
Available at: https://uzjournals.edu.uz/cce/vol2021/iss1/13