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Scientific reports of Bukhara State University

Abstract

Nanoparticles are particles made of different materials and come in variety of shapes andstructures in a size range 1 – 100 nm. Nanoparticles can be made from almost any material, including semiconductors, metals, and even structures that are organic in nature.Through, various processing techniques, nanoparticles can be multi-layered, or even hollow, allowing for avariety of uses. Plasmonic nanoparticles used in medicine have three distinct components in their design: (1) the core which is used to hold the drug, (2) theshell which protects the particle from being rejected by the immune system of the body, (3) and a surface covering of atargeting agent or drug to allow longer circulation in the body. Below we provide a fewexamples of plasmonicnanoparticles of different types, which can be practical for nanomedical procedures.This short review is based on a book recently published by Letfullin&George [1].

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References

1. Letfullin R.R., T.F. George. “Computational Nanomedicine and Nanotechnology: Lectures with Computer Practicums”.– Switzerland: Springer, 2016.– 700 p. 2. Letfullin R.R., George T.F. “PlasmonicNanomaterials in Nanomedicine,” in Springer Handbook of Nanomaterials, edited by R. Vajtai (Springer, 2013).– P. 1063-1097. 3. Letfullin R.R., George T.F. “New Dynamic Modes for Selective Laser Cancer Nanotherapy,” in Computational Studies of New Materials II: From Ultrafast Processes and Nanostructures to Optoelectronics, Energy Storage and Nanomedicine, edited by T. F. George, D. Jelski, R. R. Letfullin and G. P. Zhang (World Scientific, Singapore, 2011).– P. 131-172. 4. Letfullin R.R., C.E. W. Rice*, George T.F., Murzagulova K. “Nanoparticle-Enhanced X-Ray Therapy of Cancer,” International Journal of Theoretical Physics, Group Theory and Nonlinear Optics 17, 133-145 (2014). 5. Letfullin R.R., C.E.W. Rice*, George T. “Bone Cancer Therapy by Plasmonic Nanoparticles”. Therapeutic Delivery 2, 1259-1273 (2011). 6. Letfullin R.R., Iversen C.B.* and George T.F. “Modeling nanophotothermal therapy: kinetics of thermal ablation of healthy and cancerous cell organelles and gold nanoparticles,” Nanomedicine: Nanotechnology, Biology and Medicine 7, 137-145 (2011).

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